After he was awarded a scholarship, Howard Charles trained at the prestigious Drama Centre London. He appeared in a number of theater productions, including Macbeth, The Merchant of Venice, Twelfth Night, and Measure for Measure, among other things. He then became an established TV actor, appearing in Top Boy, The Red Line, Whitstable Pearl, The Musketeers, and, most recently, Fightland, in which he plays the main character, Duke. He also appeared in 2025 thriller movie Cleaner, which starred Daisy Ridley.